The microbiome as a source of novel therapy

The microbiome and its dysbiosis are now implicated in a broad range of conditions from diarrhoea, through diabetes, to alzheimer’s and therapies have the potential to impact health by either influencing the microbiome or communicating directly with the body through diverse inflammatory, immunological, neurological, physiological and metabolic pathways.

Microbiome research and diagnostics are developing at an incredible pace and analytical tools are now not only able to show correlations between disease states and dysbiosis but also providing evidence of a causal relationship. Pre-clinical data on microbial candidates and some clinical experience of use of probiotics in diverse indications provide proof of principal that microbial therapy can be developed to solve real medical needs.